Chimeric antigen receptor (CAR) T-cell therapy in multiple myeloma: The evolving Canadian landscape
DOI:
https://doi.org/10.58931/cht.2023.2342Abstract
Multiple myeloma (MM) is a hematologic malignancy characterized by excessive production and improper function of plasma cells. This results in an abnormal high M protein or immunoglobulin protein which can result clinically in lytic lesions, anemia, renal dysfunction, and hypercalcemia. Multiple myeloma is not curable; however, there has been a rapid evolution of therapies in the past two decades, leading to an improvement in overall survival (OS).
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